Hox genes are essential for proper embryonic development. In mammals, 39 genes are found clustered at four genomic loci, and their internal topological organization prefigures the place and time of their transcriptional activation. The mechanisms...
Nuclear and cytoplasmic puncta, including Cajal bodies and various forms or RNA granules, were first observed over a century ago. Evidence will be presented indicating that these and related puncta are organized via the reversible polymerization of low...
The Drosophila circadian clock functions within 75 pairs of brain neurons. We are expanding our understanding of their functions, including their sexually dimorphic contributions to behavior, their regulation of sleep and their circuitry. We have also...
