# Presentations Search Within Results Search Within Results search ## 23 results Show filters filter\_alt Sort by Year of PublicationAlphabetical A-Z sort ## 23 results Download 23 citations download- [BibTeX](/node/947861/export?format=bibtex) - [EndNote X3 XML](/node/947861/export?format=endnote8) - [EndNote 7 XML](/node/947861/export?format=endnote7) - [Endnote tagged](/node/947861/export?format=tagged) - [Marc](/node/947861/export?format=marc) - [PubMedId](/node/947861/export?format=pubmed_id) - [RIS](/node/947861/export?format=ris) ### 2016 2016. “[Of HOX and TADs: The Genetic Basis of Pre-Formation](/presentations/hox-and-tads-genetic-basis-pre-formation)” 2016. “[Of HOX and TADs: The Genetic Basis of Pre-Formation](/presentations/hox-and-tads-genetic-basis-pre-formation)” - add\_circle\_outline do\_not\_disturb\_on Abstract Hox genes are essential for proper embryonic development. In mammals, 39 genes are found clustered at four genomic loci, and their internal topological organization prefigures the place and time of their transcriptional activation. The mechanisms... 2016. “[Life Without Heterochromatin: Insights into Stabilizing the Genome](/presentations/life-without-heterochromatin-insights-stabilizing-genome)” 2016. “[Life Without Heterochromatin: Insights into Stabilizing the Genome](/presentations/life-without-heterochromatin-insights-stabilizing-genome)” - add\_circle\_outline do\_not\_disturb\_on Abstract Histone H3K9 methylation is a conserved modification that correlates broadly with gene repression in organisms ranging from fission yeast to man. In C. elegans, di- and tri-K9 methylation is abundant on repetitive elements (RE), including both transposons... ### 2015 2015. “[Regulatory Architecture of a Bacterial Cell Cycle](/presentations/regulatory-architecture-bacterial-cell-cycle-0)” 2015. “[Regulatory Architecture of a Bacterial Cell Cycle](/presentations/regulatory-architecture-bacterial-cell-cycle-0)” - add\_circle\_outline do\_not\_disturb\_on Abstract The cell cycle control logic in Caulobacter drives an integrated system that operates in time and space. Oscillating levels of a small number of temporally-controlled master regulators enable multiple cell cycle functions. Cell cycle regulation is, to a... 2015. “[The Circadian Clock and Sleep in Flies: Molecules, Neurons and Circuits](/presentations/circadian-clock-and-sleep-flies-molecules-neurons-and-circuits)” 2015. “[The Circadian Clock and Sleep in Flies: Molecules, Neurons and Circuits](/presentations/circadian-clock-and-sleep-flies-molecules-neurons-and-circuits)” - add\_circle\_outline do\_not\_disturb\_on Abstract The *Drosophila* circadian clock functions within 75 pairs of brain neurons. We are expanding our understanding of their functions, including their sexually dimorphic contributions to behavior, their regulation of sleep and their circuitry. We have also... 2015. “[TRP Channels and Pain: From Physiology to Atomic Structure](/presentations/trp-channels-and-pain-physiology-atomic-structure)” 2015. “[TRP Channels and Pain: From Physiology to Atomic Structure](/presentations/trp-channels-and-pain-physiology-atomic-structure)” - add\_circle\_outline do\_not\_disturb\_on Abstract Pungent irritants from pepper, mint, and mustard plants have served as powerful pharmacological probes for identifying molecules, cells, and circuits that contribute to somatosensation and pain. These natural products elicit pain by targeting members of... ### 2014 2014. “[Viral Noncoding RNAs: Insights into Evolution](/presentations/%E2%80%9Cviral-noncoding-rnas-insights-evolution%E2%80%9D)” 2014. “[Viral Noncoding RNAs: Insights into Evolution](/presentations/%E2%80%9Cviral-noncoding-rnas-insights-evolution%E2%80%9D)” - add\_circle\_outline do\_not\_disturb\_on Abstract Like host cells, some viruses produce noncoding RNAs that contribute to the viral life cycle or help the virus evade the defenses the host organism raises against infection. We have been studying a variety of noncoding RNAs made by gamma herpesviruses, a... 2014. “[New Enzymes by Evolution: Expanding Nature’s Catalytic Repertoire](/presentations/%E2%80%9Cnew-enzymes-evolution-expanding-nature%E2%80%99s-catalytic-repertoire%E2%80%9D)” 2014. “[New Enzymes by Evolution: Expanding Nature’s Catalytic Repertoire](/presentations/%E2%80%9Cnew-enzymes-evolution-expanding-nature%E2%80%99s-catalytic-repertoire%E2%80%9D)” - add\_circle\_outline do\_not\_disturb\_on Abstract Enzymes are admired for their ability to selectively catalyze myriad transformations. We use laboratory evolution experiments to understand better how evolution modifies existing enzymes and creates new ones. A powerful approach to engineering biological... 2014. “[Biological Recognition and the Control of Protein Stability](/presentations/%E2%80%9Cbiological-recognition-and-control-protein-stability%E2%80%9D)” 2014. “[Biological Recognition and the Control of Protein Stability](/presentations/%E2%80%9Cbiological-recognition-and-control-protein-stability%E2%80%9D)” - add\_circle\_outline do\_not\_disturb\_on Abstract **Marc W. Kirschner, Ph.D.** John Franklin Enders University Professor Chair and Professor of Systems Biology Harvard Medical School ### 2013 2013. “[Quantitative Analysis of Actin Dynamics During Cellular Motility, Endocytosis and Cytokinesis](/presentations/quantitative-analysis-actin-dynamics-during-cellular-motility-endocytosis-and)” 2013. “[Quantitative Analysis of Actin Dynamics During Cellular Motility, Endocytosis and Cytokinesis](/presentations/quantitative-analysis-actin-dynamics-during-cellular-motility-endocytosis-and)” - add\_circle\_outline do\_not\_disturb\_on Abstract We study the molecular basis of cellular motility, endocytosis and cytokinesis. We use fission yeast for much of this work because they use the same molecular mechanisms at humans, but are much more amenable to experimentation using molecular genetics. We... 2013. “[Physical Mechanisms of Cell Organization on Micron Length Scales](/presentations/%E2%80%9Cphysical-mechanisms-cell-organization-micron-length-scales%E2%80%9D)” 2013. “[Physical Mechanisms of Cell Organization on Micron Length Scales](/presentations/%E2%80%9Cphysical-mechanisms-cell-organization-micron-length-scales%E2%80%9D)” - add\_circle\_outline do\_not\_disturb\_on Abstract Cells are organized on length scales from Angstroms to microns. However, the mechanisms by which Angstrom-scale molecular properties are translated to micron-scale macroscopic properties are not well understood. We have shown that interactions between... 2013. “[Bioorthogonal Chemistry, an Enabling Tool for Biology and Drug Development](/presentations/bioorthogonal-chemistry-enabling-tool-biology-and-drug-development)” 2013. “[Bioorthogonal Chemistry, an Enabling Tool for Biology and Drug Development](/presentations/bioorthogonal-chemistry-enabling-tool-biology-and-drug-development)” - add\_circle\_outline do\_not\_disturb\_on Abstract The molecular details of biological processes can be most accurately understood by probing biomolecules within their native habitats in cells, or even better, live organisms. To interrogate biomolecules in such complex settings requires the means to... 2013. “[New Ideas about Old Problems in Cell Organization and Regulation](/presentations/steven-l-mcknight-april-11-2013-bloch-lecture-konrad-bloch-lecture-hosted)” 2013. “[New Ideas about Old Problems in Cell Organization and Regulation](/presentations/steven-l-mcknight-april-11-2013-bloch-lecture-konrad-bloch-lecture-hosted)” - add\_circle\_outline do\_not\_disturb\_on Abstract Nuclear and cytoplasmic puncta, including Cajal bodies and various forms or RNA granules, were first observed over a century ago. Evidence will be presented indicating that these and related puncta are organized via the reversible polymerization of low... - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [ Next page chevron\_right ](?page=1 "Go to next page")