#  Bloch Lectures 

 



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### 2016

2016. “[Of HOX and TADs: The Genetic Basis of Pre-Formation](/presentations/hox-and-tads-genetic-basis-pre-formation)”



 

 

2016. “[Of HOX and TADs: The Genetic Basis of Pre-Formation](/presentations/hox-and-tads-genetic-basis-pre-formation)”



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Hox genes are essential for proper embryonic development. In mammals, 39 genes are found clustered at four genomic loci, and their internal topological organization prefigures the place and time of their transcriptional activation. The mechanisms...



 

 

 

 



### 2015

2015. “[The Circadian Clock and Sleep in Flies: Molecules, Neurons and Circuits](/presentations/circadian-clock-and-sleep-flies-molecules-neurons-and-circuits)”



 

 

2015. “[The Circadian Clock and Sleep in Flies: Molecules, Neurons and Circuits](/presentations/circadian-clock-and-sleep-flies-molecules-neurons-and-circuits)”



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
The *Drosophila* circadian clock functions within 75 pairs of brain neurons. We are expanding our understanding of their functions, including their sexually dimorphic contributions to behavior, their regulation of sleep and their circuitry. We have also...



 

 

 

 



### 2014

2014. “[Biological Recognition and the Control of Protein Stability](/presentations/%E2%80%9Cbiological-recognition-and-control-protein-stability%E2%80%9D)”



 

 

2014. “[Biological Recognition and the Control of Protein Stability](/presentations/%E2%80%9Cbiological-recognition-and-control-protein-stability%E2%80%9D)”



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
**Marc W. Kirschner, Ph.D.**   
John Franklin Enders University Professor   
Chair and Professor of Systems Biology   
Harvard Medical School

 



 

 

 

 



### 2013

2013. “[New Ideas about Old Problems in Cell Organization and Regulation](/presentations/steven-l-mcknight-april-11-2013-bloch-lecture-konrad-bloch-lecture-hosted)”



 

 

2013. “[New Ideas about Old Problems in Cell Organization and Regulation](/presentations/steven-l-mcknight-april-11-2013-bloch-lecture-konrad-bloch-lecture-hosted)”



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Nuclear and cytoplasmic puncta, including Cajal bodies and various forms or RNA granules, were first observed over a century ago. Evidence will be presented indicating that these and related puncta are organized via the reversible polymerization of low...



 

 

 

 



### 2011

2011. “[The Role of Science, Technology and Innovation in Solving the Energy Challenge”](/presentations/%E2%80%9C-role-science-technology-and-innovation-solving-energy-challenge%E2%80%9D)”



 

 

2011. “[The Role of Science, Technology and Innovation in Solving the Energy Challenge”](/presentations/%E2%80%9C-role-science-technology-and-innovation-solving-energy-challenge%E2%80%9D)”



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
**Steven Chu**  
United States Secretary of Energy